For most people night is a time of rest and renewal, however, for many people with Parkinson’s disease (PD) night all too often brings anything but.The reasons for nighttime difficulties are multiple and complex, and, until recently, were not well understood.Sleep apnea (or obstructive sleep apnea) is the most common sleep-related breathing disorder.The prevalence (the number of persons with this condition in a given group) of sleep apnea increases with age and it is a known cause of mortality in the elderly.
Alcohol use: additive CNS depression• Tell patient he may take with or without food.
Although there were no definitive conclusions with respect to comparisons among agents, there was some indication that newer agents (solifenacin) may have greater efficacy than slightly older agents (tolterodine) for some outcomes.
Oxybutynin was the only agent with a higher risk of withdrawals versus placebo.
Ironically, older adults (and their spouses) are less likely to complain about their sleep apnea symptoms such as snoring, gasping, choking, and shortness of breath.
At least one study has suggested that up to 20% of persons with Parkinson’s Disease have significant sleep apnea compared to less than 5% of older adults without PD.